| 3rd Qualifying Round | Play-offs | Group Stage | Knockout round | Round of 16 | Quarterfinals |
| Semifinals | Final |
Round:
Played
1st Round
09/15/2021 - Wednesday
10:30
Spartak Moscow
0
x
1
Legia Warsaw
09/16/2021 - Thursday
15:00
Leicester City
2
x
2
Napoli
2nd Round
09/30/2021 - Thursday
12:45
Legia Warsaw
1
x
0
Leicester City
12:45
Napoli
2
x
3
Spartak Moscow
3rd Round
10/20/2021 - Wednesday
10:30
Spartak Moscow
3
x
4
Leicester City
10/21/2021 - Thursday
15:00
Napoli
3
x
0
Legia Warsaw
4th Round
11/04/2021 - Thursday
13:45
Legia Warsaw
1
x
4
Napoli
16:00
Leicester City
1
x
1
Spartak Moscow
5th Round
11/24/2021 - Wednesday
10:30
Spartak Moscow
2
x
1
Napoli
11/25/2021 - Thursday
15:00
Leicester City
3
x
1
Legia Warsaw
6th Round
12/09/2021 - Thursday
12:45
Legia Warsaw
0
x
1
Spartak Moscow
12:45
Napoli
3
x
2
Leicester City