| Preliminary Round | 1st Qualifying Round | 2nd Qualifying Round | 3rd Qualifying Round | Play-offs | Group Stage |
| 16th Finals | 8th Finals | Quarterfinals | Semifinals | Final |
Round:
Played
1st Round
04/08/2021 - Thursday
15:00
Ajax
1
x
2
Roma
15:00
Arsenal
1
x
1
Slavia Praha
15:00
Dinamo Zagreb
0
x
1
Villarreal
15:00
Granada
0
x
2
Manchester United
2nd Round
04/15/2021 - Thursday
15:00
Manchester United
2
x
0
Granada
15:00
Roma
1
x
1
Ajax
15:00
Slavia Praha
0
x
4
Arsenal
15:00
Villarreal
2
x
1
Dinamo Zagreb