| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas | Quartas |
| Semi | Final |
Round:
Played
1st Round
04/06/2022 - Wednesday
20:00
Deportivo Tachira
0
x
4
Palmeiras-SP
22:00
Independiente Petrolero
1
x
1
Emelec
2nd Round
04/12/2022 - Tuesday
20:30
Palmeiras-SP
8
x
1
Independiente Petrolero
04/14/2022 - Thursday
22:00
Emelec
1
x
1
Deportivo Tachira
3rd Round
04/26/2022 - Tuesday
18:15
Independiente Petrolero
1
x
2
Deportivo Tachira
04/27/2022 - Wednesday
20:00
Emelec
1
x
3
Palmeiras-SP
4th Round
05/03/2022 - Tuesday
18:15
Deportivo Tachira
1
x
4
Emelec
20:30
Independiente Petrolero
0
x
5
Palmeiras-SP
5th Round
05/18/2022 - Wednesday
18:00
Palmeiras-SP
1
x
0
Emelec
20:00
Deportivo Tachira
3
x
0
Independiente Petrolero
6th Round
05/24/2022 - Tuesday
20:30
Emelec
7
x
0
Independiente Petrolero
20:30
Palmeiras-SP
4
x
1
Deportivo Tachira