| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas | Quartas |
| Semi | Final |
Round:
Played
1st Round
06/28/2022 - Tuesday
18:15
Emelec
1
x
1
Atlético-MG
20:30
Atlético-PR
2
x
1
Libertad
20:30
Corinthians-SP
0
x
0
Boca Juniors
06/29/2022 - Wednesday
18:15
Cerro Porteño
0
x
3
Palmeiras-SP
18:15
Talleres
1
x
1
Colón
20:30
Tolima
0
x
1
Flamengo-RJ
20:30
Vélez Sarsfield
1
x
0
River Plate
06/30/2022 - Thursday
20:30
Fortaleza-CE
1
x
1
Estudiantes
2nd Round
07/05/2022 - Tuesday
18:15
Atlético-MG
1
x
0
Emelec
20:30
Boca Juniors
0
Pen
0*
Corinthians-SP
20:30
Libertad
1
x
1
Atlético-PR
07/06/2022 - Wednesday
18:15
Colón
0
x
2
Talleres
18:15
Palmeiras-SP
5
x
0
Cerro Porteño
20:30
Flamengo-RJ
7
x
1
Tolima
20:30
River Plate
0
x
0
Vélez Sarsfield
07/07/2022 - Thursday
20:30
Estudiantes
3
x
0
Fortaleza-CE