| 1a Fase | Fase de Grupos | Oitavas | Quartas | Semi | Final |
Round:
Played
1st Round
07/13/2021 - Tuesday
18:15
LDU
0
x
1
Grêmio-RS
20:30
América de Cali
0
x
1
Atlético-PR
07/14/2021 - Wednesday
18:15
Sporting Cristal
2
x
1
Arsenal Sarandí
20:30
Independiente del Valle
0
x
2
Bragantino-SP
20:30
Junior Barranquilla
3
x
4
Libertad
07/15/2021 - Thursday
18:15
Santos-SP
1
x
0
Independiente
20:30
Deportivo Tachira
2
x
2
Rosario Central
20:30
Nacional-URU
1
x
2
Peñarol
2nd Round
07/20/2021 - Tuesday
18:15
Grêmio-RS
1
x
2
LDU
20:30
Atlético-PR
4
x
1
América de Cali
07/21/2021 - Wednesday
18:15
Arsenal Sarandí
1
x
1
Sporting Cristal
20:30
Bragantino-SP
1
x
1
Independiente del Valle
20:30
Libertad
0
x
1
Junior Barranquilla
07/22/2021 - Thursday
18:15
Independiente
1
x
1
Santos-SP
20:30
Peñarol
0
x
1
Nacional-URU
20:30
Rosario Central
1
x
0
Deportivo Tachira