| 1a Fase | Fase de Grupos | Oitavas | Quartas | Semi | Final |
Round:
Played
1st Round
06/28/2022 - Tuesday
18:15
Nacional-URU
2
x
0
Unión de Santa Fe
20:30
Colo-Colo
2
x
0
Internacional-RS
06/29/2022 - Wednesday
18:15
The Strongest
1
x
2
Ceará-CE
20:30
Deportivo Cali
0
x
0
Melgar
20:30
Deportivo Tachira
1
x
1
Santos-SP
06/30/2022 - Thursday
18:15
Independiente del Valle
2
x
1
Lanús
20:30
Olimpia
2
x
0
Atlético-GO
20:30
Universidad Católica
2
x
4
São Paulo-SP
2nd Round
07/05/2022 - Tuesday
18:15
Unión de Santa Fe
1
x
2
Nacional-URU
20:30
Internacional-RS
4
x
1
Colo-Colo
07/06/2022 - Wednesday
18:15
Ceará-CE
3
x
0
The Strongest
20:30
Melgar
2
x
1
Deportivo Cali
20:30
Santos-SP
1
Pen
1*
Deportivo Tachira
07/07/2022 - Thursday
18:15
Lanús
0
x
0
Independiente del Valle
20:30
Atlético-GO
*2
Pen
0
Olimpia
20:30
São Paulo-SP
4
x
1
Universidad Católica