| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas de Final | Quartas de Final |
| Semifinal | Final |
Round:
Played
1st Round
01/30/2018 - Tuesday
17:15
Carabobo
1
x
0
Club Guaraní
19:30
Banfield
1
x
1
Independiente del Valle
19:30
Santiago Wanderers
1
x
1
Melgar
01/31/2018 - Wednesday
18:45
Chapecoense-SC
0
x
1
Nacional-URU
18:45
Universidad de Concepción
0
x
4
Vasco-RJ
02/01/2018 - Thursday
17:15
Deportivo Tachira
2
x
3
Santa Fe
19:30
Olimpia
1
x
0
Junior Barranquilla
19:30
Oriente Petrolero
1
x
2
Jorge Wilstermann
2nd Round
02/06/2018 - Tuesday
17:15
Club Guaraní
6
x
0
Carabobo
19:30
Independiente del Valle
2
x
2
Banfield
19:30
Melgar
0
x
1
Santiago Wanderers
02/07/2018 - Wednesday
18:45
Nacional-URU
1
x
0
Chapecoense-SC
18:45
Vasco-RJ
2
x
0
Universidad de Concepción
02/08/2018 - Thursday
19:00
Santa Fe
0
x
0
Deportivo Tachira
19:30
Jorge Wilstermann
2
x
2
Oriente Petrolero
21:15
Junior Barranquilla
3
x
1
Olimpia