| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas de Final | Quartas de Final |
| Semifinal | Final |
Round:
Played
1st Round
02/13/2018 - Tuesday
19:30
Santiago Wanderers
1
x
2
Santa Fe
02/14/2018 - Wednesday
17:00
Banfield
2
x
2
Nacional-URU
18:45
Vasco-RJ
4
x
0
Jorge Wilstermann
02/15/2018 - Thursday
17:15
Junior Barranquilla
1
x
0
Club Guaraní
2nd Round
02/20/2018 - Tuesday
19:30
Santa Fe
3
x
0
Santiago Wanderers
02/21/2018 - Wednesday
19:45
Jorge Wilstermann
4
Pen
0*
Vasco-RJ
19:45
Nacional-URU
1
x
0
Banfield
02/22/2018 - Thursday
19:30
Club Guaraní
0
x
0
Junior Barranquilla