| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas de Final | Quartas de Final |
| Semifinais | Final |
Round:
Played
1st Round
03/11/2021 - Thursday
19:30
Club Guaraní
0
x
2
Atlético Nacional
2nd Round
03/18/2021 - Thursday
20:30
Atlético Nacional
3
x
0
Club Guaraní