| 1a Fase | 2a Fase | 3a Fase | Fase de Grupos | Oitavas de Final | Quartas de Final |
| Semifinais | Final |
Round:
Played
1st Round
04/20/2021 - Tuesday
20:30
Vélez Sarsfield
2
x
3
Flamengo-RJ
04/21/2021 - Wednesday
22:00
Unión La Calera
2
x
2
LDU
2nd Round
04/27/2021 - Tuesday
18:15
Flamengo-RJ
4
x
1
Unión La Calera
18:15
LDU
3
x
1
Vélez Sarsfield
3rd Round
05/04/2021 - Tuesday
18:15
Unión La Calera
0
x
2
Vélez Sarsfield
20:30
LDU
2
x
3
Flamengo-RJ
4th Round
05/11/2021 - Tuesday
20:30
Unión La Calera
2
x
2
Flamengo-RJ
05/13/2021 - Thursday
18:00
Vélez Sarsfield
3
x
1
LDU
5th Round
05/19/2021 - Wednesday
18:00
Vélez Sarsfield
2
x
1
Unión La Calera
20:00
Flamengo-RJ
2
x
2
LDU
6th Round
05/27/2021 - Thursday
20:00
Flamengo-RJ
0
x
0
Vélez Sarsfield
20:00
LDU
5
x
2
Unión La Calera